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  • Analgesic and decongestant combination
  • Antibiotics
  • Antihistamine and analgesic combination
  • Antihistamine and decongestant combination
  • Antihistamine, analgesic and decongestant combination
  • Chinese herbs
  • Corticosteroids nasal spray
  • Echinacea
  • Ipratropium Bromide Nasal spray
  • NSAIDs
  • Vitamin C
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Treatments for Prevention and Treatment of Common Cold in Children

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Ipratropium Bromide Nasal spray (RX)

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Helpful

Common Cold treatment in Children with cold

Curefacts.com - Evidence icon EVIDENCE | REASONABLY TESTED - 7 studies with 2,144 children
Curefacts.com - Circle icon EFFECTIVENESS | EFFECTIVE for runny nose
Curefacts.com - Circle icon SAFETY | MILD RISKS
Treatment with Ipratropium Bromide Nasal Spray. 7 valid studies conducted, with 2,144 individuals. Effective in relieving runny nose. Minor side effects include dry nose and bloody nose.

NSAIDs (OTC)

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Helpful

Common Cold treatment in Children with cold

Curefacts.com - Evidence icon EVIDENCE | REASONABLY TESTED - 9 studies with 1,069 children
Curefacts.com - Circle icon EFFECTIVENESS | EFFECTIVE for fever, pains and sneezing
Curefacts.com - Circle icon SAFETY | MILD RISKS
Treatment with NSAIDs (e.g. Aspirin, Ibuprofen). 9 valid studies conducted, with 1,069 individuals. Reduces fever, pain and sneezing (but does not seem to reduce cough and runny nose) . Side effects seem minor for children.

Antihistamine and analgesic combination (OTC)

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Helpful

Common Cold treatment in Children with cold

Curefacts.com - Evidence icon EVIDENCE | NEEDS MORE TESTING - 3 studies with 1,508 children
Curefacts.com - Circle icon EFFECTIVENESS | EFFECTIVE for fever, general discomfort, pains and sneezing
Curefacts.com - Circle icon SAFETY | PROBABLY SAFE
Treatment with Antihistamine and Analgesic OTC combination. 3 valid studies conducted, with 1,508 participants. It reduces fever, pain and perhaps sneezing, and improves general feeling (but does not seem to reduce cough, runny nose, and stuffy nose) . Side effects seem minor, but the treatment is very dangerous when not sticking to permitted age and dosage.

Analgesic and decongestant combination (OTC)

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Helpful

Common Cold treatment in Children with cold

Curefacts.com - Evidence icon EVIDENCE | POORLY TESTED - 1 study with 65 children
Curefacts.com - Circle icon EFFECTIVENESS | EFFECTIVE for fever, general discomfort, pains and stuffy nose
Curefacts.com - Circle icon SAFETY | MILD RISKS
Treatment with analgesic and decongestant combination (e.g. ibuprofen and pseudoephedrine). Only 1 valid clinical trial conducted, with 65 children. Improves general feeling and Reduces fever, pain, and blockage of the nose. Side effects seem minor, including dizziness that is relatively frequent.

Antihistamine and decongestant combination (OTC)

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Insignificant

Common Cold treatment in Children with cold

Curefacts.com - Evidence icon EVIDENCE | REASONABLY TESTED - 12 studies with 1,239 children
Curefacts.com - Circle icon EFFECTIVENESS | MILD BENEFITS for cough, general discomfort, runny nose, sneezing and stuffy nose
Curefacts.com - Circle icon SAFETY | PROBABLY SAFE
Treatment with antihistamine and decongestant combination (e.g. triprolidine and pseudoephedrine). 12 valid studies conducted, with 1,239 adults and children. Improves general feeling and may slightly reduce sneezing, cough, runny nose and stuffy nose . Side effects seem minor, and include dry mouth and insomnia.

Antihistamine, analgesic and decongestant combination (OTC)

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Mixed

Common Cold treatment in Children with cold

Curefacts.com - Evidence icon EVIDENCE | POORLY TESTED - 1 study with 201 children
Curefacts.com - Circle icon EFFECTIVENESS | EFFECTIVE for fever and pains
Curefacts.com - Circle icon SAFETY | MILD RISKS
Treatment with antihistamine, analgesic and decongestant combination (e.g. Acetaminophen, Chlorpheniramine and Pseudoephedrine). Only 1 valid study conducted, with 201 children. Ineffective and unsafe for younger children. Seems safe, but no better than regular analgesic (e.g. Acetaminophen) for older children.

Vitamin C (vitamin)

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Ineffective

Common Cold prevention in healthy Children

Curefacts.com - Evidence icon EVIDENCE | NEEDS MORE TESTING - 4 studies with 1,691 children
Curefacts.com - Circle icon EFFECTIVENESS | NEGLIGIBLE BENEFITS
Curefacts.com - Circle icon SAFETY | SAFE
Prevention with Vitamin C supplement (Ascorbic acid tablets). 4 valid study conducted, with 1,691 children. Prevents only 1 in 236 Common Cold cases, or less. May slightly reduce severity of cold and speed up recovery. Seems safe.

Echinacea (alternative medicine)

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Ineffective

Common Cold treatment in Children with cold

Curefacts.com - Evidence icon EVIDENCE | POORLY TESTED - 1 study with 524 children
Curefacts.com - Circle icon EFFECTIVENESS | INEFFECTIVE
Curefacts.com - Circle icon SAFETY | MILD RISKS
Treatment with Echinacea extract (Purple coneflower). 1 study conducted, with 431 children. Does not reduce cold symptoms and does not speed up recovery. Mild side effects, rash pretty common. Dangerous for children with allergy.

Antibiotics (RX)

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Ineffective

Common Cold treatment in Children with cold

Curefacts.com - Evidence icon EVIDENCE | NEEDS MORE TESTING - 2 studies with 449 children
Curefacts.com - Circle icon EFFECTIVENESS | INEFFECTIVE
Curefacts.com - Circle icon SAFETY | MILD RISKS
treating with antibiotics (for example tetracycline). 2 studies conducted, with 449 children. Does not reduce cold symptoms and does not speed up recovery. Mild side effects, including mainly diarrhea.

Corticosteroids nasal spray (OTC)

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Unclear

Common Cold treatment in Children with cold

Curefacts.com - Evidence icon EVIDENCE | POORLY TESTED - 1 study with 100 children
Curefacts.com - Circle icon EFFECTIVENESS | UNCLEAR
Curefacts.com - Circle icon SAFETY | MILD RISKS
Treatment with Corticosteroids nose spray. Only 1 valid study conducted, with 100 children. Unclear effectiveness due to high risk of bias in the trial. Seems safe, but long term usage and higher than the recommended dosage may delay children's' growth.

Chinese herbs (alternative medicine)

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Unclear

Common Cold treatment in Children with cold

Curefacts.com - Evidence icon EVIDENCE | NEEDS MORE TESTING - 9 studies with 1,701 children
Curefacts.com - Circle icon EFFECTIVENESS | UNCLEAR
Curefacts.com - Circle icon SAFETY | UNCLEAR SAFETY
Treatment with Chinese herbal preparations. 9 studies conducted, with 1,701 children. Unclear effectiveness due to high risk of bias and inconsistent findings. Unclear safety.

Additional Information

Common Cold

Common cold, also known simply as a cold, is a viral infectious disease of the upper respiratory tract that primarily affects the nose. The throat, sinuses, and voice box may also be affected. Signs and symptoms may begin less than two days following exposure. They include coughing, sore throat, runny nose, sneezing, headache, and fever. People usually recover in seven to ten days. Some symptoms may last up to three weeks. In those with other health problems, pneumonia may occasionally develop. (source)

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