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Antihistamine and decongestant combination
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Common Cold
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Antihistamine and decongestant combination for Prevention and Treatment of Common Cold in All Ages

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Antihistamine and decongestant combination (OTC)


Insignificant

Common Cold treatment in Children with cold

EVIDENCE | REASONABLY TESTED - 12 studies with 1,239 children
EFFECTIVENESS | MILD BENEFITS for cough, general discomfort, runny nose, sneezing and stuffy nose
SAFETY | PROBABLY SAFE
Treatment with antihistamine and decongestant combination (e.g. triprolidine and pseudoephedrine). 12 valid studies conducted, with 1,239 adults and children. Improves general feeling and may slightly reduce sneezing, cough, runny nose and stuffy nose . Side effects seem minor, and include dry mouth and insomnia.

Antihistamine and decongestant combination (OTC)


Insignificant

Common Cold treatment in Adults with cold

EVIDENCE | REASONABLY TESTED - 12 studies with 1,239 adults
EFFECTIVENESS | MILD BENEFITS for cough, general discomfort, runny nose, sneezing and stuffy nose
SAFETY | PROBABLY SAFE
Treatment with antihistamine and decongestant combination (e.g. triprolidine and pseudoephedrine). 12 valid studies conducted, with 1,239 individuals. Improves general feeling and may slightly reduce sneezing, cough, runny nose and stuffy nose . Side effects seem minor, and include dry mouth, insomnia and constipation.

Antihistamine and decongestant combination (OTC)


Damaging

Common Cold treatment in Toddlers with cold

EVIDENCE | POORLY TESTED - 2 studies with 113 toddlers
EFFECTIVENESS | INEFFECTIVE
SAFETY | DANGEROUS
Treatment with Antihistamine and decongestant combination (e.g. brompheniramine and phenylpropanolamine). 2 valid studies conducted, with 113 toddlers and young children. Does not relief symptoms of Common Cold. Dangerous and life threatening for toddlers.

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Antihistamines are drugs which treat allergic rhinitis and other allergies. As an alternative to taking an antihistamine, people who suffer from allergies can instead avoid the substance which irritates them. Antihistamines are usually for short-term treatment. A decongestants, or nasal decongestant, is a type of pharmaceutical drug that is used to relieve nasal congestion in the upper respiratory tract. The active ingredient in most decongestants is either pseudoephedrine or phenylephrine. (source)
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