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Treatments for Prevention of Flu in Children

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Flu shot (vaccine)

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Insignificant

Flu prevention in healthy Children

Curefacts.com - Evidence icon EVIDENCE | WELL TESTED - 75 studies with 300,000 children
Curefacts.com - Circle icon EFFECTIVENESS | MILD BENEFITS for prevention of symptoms
Curefacts.com - Circle icon SAFETY | MILD RISKS
Flu shot vaccine with “dead” inactivated viruses. 75 studies conducted, with 300,000 children. Prevents 1 flu case in 28 vaccinated children, and 1 influenza-like-illness in 8 vaccinated children. Doesn't prevent flu complications. irritating side effects. Unclear safety.

Flu Nasal Aerosol (vaccine)

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Mixed

Flu prevention in healthy Children

Curefacts.com - Evidence icon EVIDENCE | WELL TESTED - 75 studies with 300,000 children
Curefacts.com - Circle icon EFFECTIVENESS | EFFECTIVE for prevention of symptoms
Curefacts.com - Circle icon SAFETY | DANGEROUS
Flu nose spray vaccine with “live” (weakened) viruses. 75 studies conducted, with 300,000 children. Prevents 1 flu case in 6 vaccinated children, and 1 influenza-like-illness in 12 vaccinated children. Does not prevent flu complications. Strong side effects. Known serious harms.

Neuraminidase inhibitors (RX)

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Mixed

Flu prevention in healthy Children

Curefacts.com - Evidence icon EVIDENCE | NEEDS MORE TESTING - 3 studies with 863 children
Curefacts.com - Circle icon EFFECTIVENESS | MILD BENEFITS for prevention of symptoms
Curefacts.com - Circle icon SAFETY | MILD RISKS
Preventive treatment with Neuraminidase inhibitors (e.g. zanamivir, oseltamivir). 3 studies conducted, with 863 children. Prevents 1 case of influenza transmission when given to 12 children in households were a member already has the Flu. Mild side effects, including vomiting.

Amantadine and Rimantadine (RX)

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Mixed

Flu prevention in healthy Children

Curefacts.com - Evidence icon EVIDENCE | NEEDS MORE TESTING - 5 studies with 1,007 children
Curefacts.com - Circle icon EFFECTIVENESS | MILD BENEFITS
Curefacts.com - Circle icon SAFETY | DANGEROUS
Prevention of influenza A with Amantadine and Rimantadine. 5 studies conducted, with 1,007 children. Amantadine prevents 5.88% of confirmed flu type A infections during influenza A epidemic outbreaks, while Rimantadine is ineffective. The impact of both on complications is unclear. Both drugs have irritating stomach and gut effects, while Amantadine may also impair the nervous system and lead to psychiatric symptoms.

Flu shot (vaccine)

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Unclear

Flu prevention in Children with Cancer

Curefacts.com - Evidence icon EVIDENCE | NEEDS MORE TESTING - 10 studies with 770 children
Curefacts.com - Circle icon EFFECTIVENESS | UNCLEAR
Curefacts.com - Circle icon SAFETY | MILD RISKS
Flu shot vaccine with “dead” inactivated viruses in children with cancer undergoing chemotherapy. 10 studies conducted, with 770 children. Generates a relatively mild immune response during chemotherapy. Prevention of flu symptoms and complications is unknown and was not measured. Mild side effects.

Flu shot (vaccine)

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Unclear

Flu prevention in Children with Cystic Fibrosis

Curefacts.com - Evidence icon EVIDENCE | POORLY TESTED - 4 studies with 143 children
Curefacts.com - Circle icon EFFECTIVENESS | UNCLEAR
Curefacts.com - Circle icon SAFETY | UNCLEAR SAFETY
Flu shot vaccine with “dead” inactivated viruses. 4 studies conducted, with 143 children. Unclear benefits. Irritating side effects and unclear safety.

Flu Nasal Aerosol (vaccine)

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Unclear

Flu prevention in Children with Cystic Fibrosis

Curefacts.com - Evidence icon EVIDENCE | POORLY TESTED - 2 studies with 60 children
Curefacts.com - Circle icon EFFECTIVENESS | UNCLEAR
Curefacts.com - Circle icon SAFETY | DANGEROUS
Flu nose spray vaccine with “live” (weakened) viruses. 2 studies conducted, with 60 children. Unclear benefits. Strong side effects. Known serious harms.

Additional Information

Flu

Influenza, commonly known as “the flu”, is an infectious disease caused by an influenza virus. Symptoms can be mild to severe. The most common symptoms include: a high fever, runny nose, sore throat, muscle pains, headache, coughing, and feeling tired. These symptoms typically begin two days after exposure to the virus and most last less than a week. The cough, however, may last for more than two weeks. (source)

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