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Neuraminidase inhibitors for Prevention and Treatment of Flu in All Ages

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Neuraminidase inhibitors (RX)

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Mixed

Flu treatment in Children with Flu

Curefacts.com - Evidence icon EVIDENCE | REASONABLY TESTED - 6 studies with 2,356 children
Curefacts.com - Circle icon EFFECTIVENESS | MILD BENEFITS
Curefacts.com - Circle icon SAFETY | MILD RISKS
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Treatment with Neuraminidase inhibitors (e.g. zanamivir, oseltamivir). 6 studies conducted, with 2,356 children. Shortens the duration of the Flu symptoms by 1 day on average, and may reduce ear infections. Impact on other complications remains unclear. Mild side effects, including vomiting.
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Neuraminidase inhibitors (RX)

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Mixed

Flu prevention in healthy Children

Curefacts.com - Evidence icon EVIDENCE | NEEDS MORE TESTING - 3 studies with 863 children
Curefacts.com - Circle icon EFFECTIVENESS | MILD BENEFITS for prevention of symptoms
Curefacts.com - Circle icon SAFETY | MILD RISKS
Curefacts.com - Tooltip icon Consult a Doctor
Preventive treatment with Neuraminidase inhibitors (e.g. zanamivir, oseltamivir). 3 studies conducted, with 863 children. Prevents 1 case of influenza transmission when given to 12 children in households were a member already has the Flu. Mild side effects, including vomiting.
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Neuraminidase inhibitors (RX)

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Unclear

Flu treatment in Children with Cystic Fibrosis with Flu

Curefacts.com - Evidence icon EVIDENCE | NOT TESTED
Curefacts.com - Circle icon EFFECTIVENESS | UNCLEAR
Curefacts.com - Circle icon SAFETY | DANGEROUS
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Treatment with Neuraminidase inhibitors (e.g. zanamivir, oseltamivir). No studies conducted, and therefore no data exists on benefits. Seems safe for Oseltamivir. Mild known side effects, including vomiting. Zanamivir may evoke asthma attacks and is risky for children with Cystic Fibrosis.
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Neuraminidase inhibitors (RX)

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Unclear

Flu treatment in Adults with Cystic Fibrosis with Flu

Curefacts.com - Evidence icon EVIDENCE | NOT TESTED
Curefacts.com - Circle icon EFFECTIVENESS | UNCLEAR
Curefacts.com - Circle icon SAFETY | DANGEROUS
Curefacts.com - Tooltip icon Consult a Doctor
Treatment with Neuraminidase inhibitors (e.g. zanamivir, oseltamivir). No studies conducted, and therefore no data exists on benefits. Seems safe for Oseltamivir. Mild known side effects, including vomiting. Zanamivir may evoke asthma attacks and is risky for adults with Cystic Fibrosis.
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Neuraminidase inhibitors

Neuraminidase inhibitors (NAIs) are a class of drugs which block the neuraminidase enzyme. They are commonly used as antiviral drugs because they block the function of viral neuraminidases of the influenza virus, by preventing its reproduction by budding from the host cell. Oseltamivir (Tamiflu) a prodrug, Zanamivir (Relenza), Laninamivir (Inavir), and Peramivir belong to this class. (source)

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