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Live intranasal Influenza Vaccine for Prevention and Treatment of Flu in All Ages

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Live intranasal Influenza Vaccine (vaccine)

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Insignificant

Flu prevention in healthy Adults

Curefacts.com - Evidence icon EVIDENCE | WELL TESTED - 69 studies with 70,000 adults
Curefacts.com - Circle icon EFFECTIVENESS | MILD BENEFITS for prevention of symptoms
Curefacts.com - Circle icon SAFETY | MILD RISKS
Flu nose spray vaccine with “live” (weakened) viruses. 69 studies conducted, with 70,000 adults. Prevents 1 flu case in 39 vaccinated adults, and 1 influenza-like-illness in 46 vaccinated adults. Does not prevent flu complications. Strong side effects, and riskier than vaccines with “dead” inactivated viruses.

Live intranasal Influenza Vaccine (vaccine)

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Mixed

Flu prevention in healthy Children

Curefacts.com - Evidence icon EVIDENCE | WELL TESTED - 75 studies with 300,000 children
Curefacts.com - Circle icon EFFECTIVENESS | EFFECTIVE for prevention of symptoms
Curefacts.com - Circle icon SAFETY | DANGEROUS
Flu nose spray vaccine with “live” (weakened) viruses. 75 studies conducted, with 300,000 children. Prevents 1 flu case in 6 vaccinated children, and 1 influenza-like-illness in 12 vaccinated children. Does not prevent flu complications. Strong side effects. Known serious harms.

Live intranasal Influenza Vaccine (vaccine)

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Damaging

Flu prevention in healthy Toddlers

Curefacts.com - Evidence icon EVIDENCE | NOT TESTED
Curefacts.com - Circle icon EFFECTIVENESS | UNCLEAR
Curefacts.com - Circle icon SAFETY | DANGEROUS
Flu nose spray vaccine with “live” (weakened) viruses. No valid studies conducted, probably since it is regarded as too risky for toddlers. Therefore, no data exists on benefits. High risk potential. Known serious harms.

Live intranasal Influenza Vaccine (vaccine)

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Damaging

Flu prevention in healthy Seniors

Curefacts.com - Evidence icon EVIDENCE | NOT TESTED
Curefacts.com - Circle icon EFFECTIVENESS | UNCLEAR
Curefacts.com - Circle icon SAFETY | DANGEROUS
Flu nose spray vaccine with “live” (weakened) viruses. Not tested with seniors, since it is considered risky. Therefore no data about benefits or risks exists. High risk potential.

Live intranasal Influenza Vaccine (vaccine)

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Unclear

Flu prevention in Children with Cystic Fibrosis

Curefacts.com - Evidence icon EVIDENCE | POORLY TESTED - 2 studies with 60 children
Curefacts.com - Circle icon EFFECTIVENESS | UNCLEAR
Curefacts.com - Circle icon SAFETY | DANGEROUS
Flu nose spray vaccine with “live” (weakened) viruses. 2 studies conducted, with 60 children. Unclear benefits. Strong side effects. Known serious harms.

Live intranasal Influenza Vaccine (vaccine)

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Unclear

Flu prevention in Adults with Cystic Fibrosis

Curefacts.com - Evidence icon EVIDENCE | POORLY TESTED - 2 studies with 36 adults
Curefacts.com - Circle icon EFFECTIVENESS | UNCLEAR
Curefacts.com - Circle icon SAFETY | UNCLEAR SAFETY
Flu nose spray vaccine with “live” (weakened) viruses. 2 studies conducted, with 36 adults. Unclear benefits. Irritating side effects and unclear safety. Riskier than flu vaccines with “dead” inactivated viruses.

Additional Information

Live intranasal Influenza Vaccine

Live attenuated influenza vaccine (LAIV) is a type of influenza vaccine in the form of a nasal spray. It is an attenuated vaccine, unlike most influenza vaccines, which are inactivated vaccines. LAIV is administered intranasally, while inactivated vaccines are administered by intramuscular injection. Both live attenuated and inactivated vaccines are typically trivalent, since they contain material from three different influenza virus. LAIV is sold under the trade name FluMist in the United States and Canada. (source)

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