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Flu Nasal Aerosol (vaccine) for prevention of Flu in healthy Adults

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    Insignificant

    Bottom Line

  • Flu nose spray vaccine with “live” (weakened) viruses. 69 studies conducted, with 70,000 adults. Prevents 1 flu case in 39 vaccinated adults, and 1 influenza-like-illness in 46 vaccinated adults. Does not prevent flu complications. Strong side effects, and riskier than vaccines with “dead” inactivated viruses.

    • Curefacts.com -  Evidence icon EVIDENCE | WELL TESTED
    • Curefacts.com -  Effectiveness icon EFFECTIVENESS | MILD BENEFITS
    • Curefacts.com -  Safety Circle icon SAFETY | MILD RISKS

Recommendations

Do not use this treatment:

It prevents flu infection for 2.6% of the vaccinated adults, but it does not prevent complications. It has Strong side effects and may be risky. Consider the flu shot instead.

Doctors Say That Curefacts.com -  Tooltip icon

Note that the information here relates only to HEALTHY adults. Flu vaccines are, for example, essential for asthmatic adults.

About Flu Nasal Aerosol (vaccine)

Flu nose spray vaccine with “live” (weakened) viruses

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    Target Population:

    healthy Adults, 16 to 65 years old

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    Dosage:

    Seasonal vaccine (once a year). 0.2 mL. One dose.

  • Curefacts.com - Goal icon

    Goal:

    Prevention of Influenza infection, symptoms and complications.

Research Summary

  • Curefacts.com - Green Pages icon Well tested
  • 69 Clinical Studies
  • 70,000 Curefacts.com - Tooltip icon Adults Tested
  • Mild benefits
  • Benefits:

    Prevents 1 case of influenza infection when the vaccine is given to 39 adults. Prevent 1 influenza-like-illness (including similar symptoms due to other viruses and causes) when the vaccine is given to 46 adults. Does not prevent complications.

  • Curefacts.com - Safety icon Mild risks
  • Risks:

    Unclear. Strong side effects: runny nose, sore throat, cough, headache, fever, chills, muscle aches. No evidence for serious harms, but reporting bias may exists and more research is needed.

Influenza virus infection Overview

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    Medical problem:

    Flu (influenza virus infection and symptoms).

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    Symptoms and signs:

    Cough, dizziness, fever, headache, nausea, pains, runny nose, sore throat, vomiting and aches.

  • Curefacts.com - Complications icon

    Complications:

    Ear infection, lung infection, Seizures.

Brand Names

Flu Nose Spray (vaccine)

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Additional Information

Flu Nasal Aerosol

Live attenuated influenza vaccine (LAIV) is a type of influenza vaccine in the form of a nasal spray. It is an attenuated vaccine, unlike most influenza vaccines, which are inactivated vaccines. LAIV is administered intranasally, while inactivated vaccines are administered by intramuscular injection. Both live attenuated and inactivated vaccines are typically trivalent, since they contain material from three different influenza virus. LAIV is sold under the trade name FluMist in the United States and Canada. (source)

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