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Antihistamine and decongestant combination (OTC) for treatment of Common Cold in Toddlers with cold

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    Damaging

    Bottom Line

  • Treatment with Antihistamine and decongestant combination (e.g. brompheniramine and phenylpropanolamine). 2 valid studies conducted, with 113 toddlers and young children. Does not relief symptoms of Common Cold. Dangerous and life threatening for toddlers.

    • Curefacts.com -  Evidence icon EVIDENCE | POORLY TESTED
    • Curefacts.com -  Effectiveness icon EFFECTIVENESS | INEFFECTIVE
    • Curefacts.com -  Safety Circle icon SAFETY | DANGEROUS
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Recommendations

Avoid this treatment:

It is ineffective and not recommended for toddlers. It is dangerous and may be even fatal to very young children.

Doctors Say That Curefacts.com -  Tooltip icon

Note that while infections with various strains of Corona viruses are responsible for most cases of common cold, the new corona virus strain, SARS-CoV-2, leads to an entirely different coronavirus infectious disease, COVID-19. The research of treatments for COVID-19 is still pre mature and not based on solid evidence. Therefore, at this stage, we can only speculate that effective treatments for common cold (and related Corona virus strains) may prove effective for Corona disease 2019 (COVID-19) and the related SARS-CoV-2 strain. Please don't count on it.

About Antihistamine and decongestant combination (OTC)

For example: a combination of Brompheniramine and Phenylpropanolamine

  • Curefacts.com - Population icon

    Target Population:

    Toddlers with cold, 6 to 24 months

  • Curefacts.com - Dosage icon

    Dosage:

    Varies according to combination, age and weight.

  • Curefacts.com - Goal icon

    Goal:

    Treatment of Common Cold symptoms

Research Summary

  • Curefacts.com - Green Pages icon Poorly tested
  • 2 Clinical Studies
  • 113 Curefacts.com - Tooltip icon Toddlers Tested
  • Ineffective
  • Benefits:

    Ineffective in overall improvement, stuffy nose and runny nose, according to the two valid clinical trials that were done.

  • Curefacts.com - Safety icon Dangerous
  • Risks:

    Cough and cold medicines not recommended for toddlers, and may be very dangerous. No side effects were found in the only trial that looked for side effects.

Common Cold Overview

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    Medical problem:

    Common Cold (symptoms caused by viral infection of the upper respiratory system).

  • Curefacts.com - Sumptoms icon

    Symptoms and signs:

    Cough, general discomfort, headache, runny nose, sneezing, sore throat, stuffy nose and weakness.

  • Curefacts.com - Complications icon

    Complications:

    Bacterial infections: lung infection, middle ear infection, strep throat, sinus infection.

Other Treatments

Brand Names

Antihistamine and decongestant combination (OTC)

  • Alavert
  • Allerfrim
  • Allerphed
  • Altafed
  • Aphedrid
  • A-Phedrin
  • Aprodine
  • Biofed-PE
  • Claritin-D
  • Conex
  • Drixoral
  • Genac
  • Histafed
  • Hist-PSE
  • Loratadine-D
  • Pediatex TD
  • Trip-PSE
  • Vi-Sudo
  • Zymine-D

Additional Information

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