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Charcot Marie Tooth disease
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Vitamin C (vitamin) for treatment of Charcot Marie Tooth disease in Children with Charcot Marie Tooth disease

  • Ineffective

    Bottom Line

  • Treatment with Vitamin C (Ascorbic acid tablets). Seems ineffective, and does not relief symptoms, according to a high quality study with 80 children. More research may be needed. Seems safe.

    • EVIDENCE | POORLY TESTED
    • EFFECTIVENESS | INEFFECTIVE
    • SAFETY | SAFE

Recommendations

Do not use this treatment:

It seems ineffective and does not seem to ease off the symptoms of CMT. Side effects seem minor.

Doctors Say That

Any excess of Vitamin C (Ascorbic acid) is evacuated from our body through the urine. This makes vitamin C pretty safe even in high dosages.

About Vitamin C (vitamin)

Ascorbic Acid tablets

  • Target Population:

    Children with Charcot Marie Tooth disease, 2 to 16 years old

  • Dosage:

    375-1,625 mg per day (adjusted to age and body weight).

  • Goal:

    Treatments of Charcot Marie Tooth disease symptoms (hereditary motor and sensory neuropathy)

Research Summary

  • Poorly tested
  • 1 Clinical Studies
  • 80 Children Tested
  • Ineffective
  • Benefits:

    Ineffective, does not ease symptoms, according to a one year high quality study. Longer research may be needed.

  • Safe
  • Risks:

    Up to 2 grams of Vitamin C per day seems safe for children and has no side effects. Doctor consultation is needed for diabetic adults or when in taking iron.

Charcot-Marie-Tooth (CMT) disease Overview

  • Medical problem:

    Charcot Marie Tooth disease (hereditary motor and sensory neuropathy)

  • Symptoms and signs:

    Decreased ability to run, decreased sensation in legs, foot drop, frequent tripping, hammer toe, high foot arches, higher than normal steps, loss of feeling in legs, muscle pain, stork leg, weakness in the forearms, weakness in the hands and weakness in the legs.

  • Complications:

    Difficulties to walk, injuries, difficulties to breath, swallow or speak

Other Treatments

Brand Names

Vitamin C (supplement)

  • Ascoltin
  • Ascot
  • C-500 Chewable Tablet
  • C-Time
  • Cecon Drops
  • Centrum Singles - Vitamin C
  • Cevi-Bid
  • Sunkist Vitamin C
  • Vicks Vitamin C Drops
  • Ester-C
  • Vasoflex HD
  • Acerola
  • Ascocid
  • Ascor L 500
  • Ascorbic Acid Quick Melts
  • Betac
  • Cemill
  • Cenolate

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Vitamin C, also known as ascorbic acid and L-ascorbic acid, is a vitamin found in food and used as a dietary supplement. As a supplement it is used to treat and prevent scurvy. Evidence does not support use in the general population for the prevention of the common cold. It may be taken by mouth or by injection. It is generally well tolerated. Vitamin C was discovered in 1912, isolated in 1928, and first made in 1933. (source)
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