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Neuraminidase inhibitors (RX) for treatment of Flu in Adults with Cystic Fibrosis with Flu

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    Unclear

    Bottom Line

  • Treatment with Neuraminidase inhibitors (e.g. zanamivir, oseltamivir). No studies conducted, and therefore no data exists on benefits. Seems safe for Oseltamivir. Mild known side effects, including vomiting. Zanamivir may evoke asthma attacks and is risky for adults with Cystic Fibrosis.

    • Curefacts.com -  Evidence icon EVIDENCE | NOT TESTED
    • Curefacts.com -  Effectiveness icon EFFECTIVENESS | UNCLEAR
    • Curefacts.com -  Safety Circle icon SAFETY | DANGEROUS

Recommendations

Do not use this treatment:

No data exists on the benefits. Side effects seem mild for Oseltamivir, while Zanamivir is risky for CF patients.

Doctors Say That Curefacts.com -  Tooltip icon

Works best if taken within 2 days of having flu symptoms, and should be taken for 5 consecutive days.

About Neuraminidase inhibitors (RX)

For example: Oseltamivir (Tamiflu), Zanamivir (Relenza)

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    Target Population:

    Adults with Cystic Fibrosis, 16 to 65 years old

  • Curefacts.com - Dosage icon

    Dosage:

    Varies according to treatment. Usually 2 mg/kg, twice-daily, for 5 days. Zanamivir usually 10 mg, twice-daily, for 5 days.

  • Curefacts.com - Goal icon

    Goal:

    Treatment of Influenza infection, symptoms and complications

Research Summary

  • Curefacts.com - Green Pages icon Not tested
  • Clinical Studies
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  • Unclear
  • Benefits:

    Unknown. No valid clinical trials.

  • Curefacts.com - Safety icon Dangerous
  • Risks:

    Common side effects include vomiting, diarrhea, nausea, headache, nosebleeds and trouble sleeping. Rare side effects may include psychiatric symptoms, trouble breathing and seizures. Zanamivir is risky for adults with Cystic Fibrosis, as it may lead to Asthma attacks.

Influenza virus infection Overview

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    Medical problem:

    Flu (influenza virus infection and symptoms).

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    Symptoms and signs:

    Cough, dizziness, fever, headache, nausea, pains, runny nose, sore throat, vomiting and aches.

  • Curefacts.com - Complications icon

    Complications:

    Ear infection, lung infection, Seizures.

Other Treatments

Brand Names

Neuraminidase inhibitors (RX)

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