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Flu shot
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Flu shot (vaccine) for prevention of Flu in Adults with Cystic Fibrosis

  • Unclear

    Bottom Line

  • Flu shot vaccine with “dead” inactivated viruses. 2 studies conducted, with 36 adults. Unclear benefits. Irritating side effects and unclear safety.

    • EVIDENCE | POORLY TESTED
    • EFFECTIVENESS | UNCLEAR
    • SAFETY | UNCLEAR SAFETY

Recommendations

Avoid this treatment:

No data exists on benefits. More research is needed. High probability for side effects.

About Flu shot (vaccine)

Flu shot vaccine with “dead” inactivated viruses

  • Target Population:

    Adults with Cystic Fibrosis, 16 to 65 years old

  • Dosage:

    Seasonal vaccine (once a year). Most brands - 0.5 mL (Fluzone - 0.25 mL, Fluzone Intradermal - 0.1 mL). One dose.

  • Goal:

    Prevention of Influenza infection, symptoms and complications.

Research Summary

  • Poorly tested
  • 2 Clinical Studies
  • 36 Adults Tested
  • Unclear
  • Benefits:

    Unclear. It does evoke immune system response, but it is not clear if this response brings actual benefits (prevention of flu symptoms and flu complications).

  • Unclear safety
  • Risks:

    Unclear. More research needed. The studies resulted high frequency of side effects, but none were life threatening or persistent. Irritating side effects include: soreness, redness, and/or swelling from the shot; headache, fever, cough, nausea, muscle aches, itching, sore eyes.

Influenza virus infection Overview

  • Medical problem:

    Flu (influenza virus infection and symptoms).

  • Symptoms and signs:

    Cough, dizziness, fever, headache, nausea, pains, runny nose, sore throat, vomiting and aches.

  • Complications:

    Ear infection, lung infection, Seizures.

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Influenza vaccines, also known as flu shots or flu jabs, are vaccines that protect against infection by influenza virus. A new version of the vaccine is developed twice a year as the influenza virus rapidly changes.Their effectiveness varies from year to year. The effectiveness in those under two years old and over 65 years old is unknown due to the low quality of the research. (source)
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