Treatment of Influenza A with Amantadine and Rimantadine. This treatment has been replaced by neuraminidase inhibitors and is no longer used in the USA. 13 studies conducted, with 1,151 adults. Shortened the duration of fever by about one day. Unknown impact on complications. Both drugs have irritating stomach and gut effects, while Amantadine may also impair the nervous system and lead to psychiatric symptoms.
Avoid this treatment:
Proven benefits include only avoiding one day of fever, while side effects are often irritating for both treatments, and are pretty dangerous for Amantadine.
Sometimes no treatment is the best treatment…
Antiviral drugs (Symmetrel and Flumadine)
Adults with Flu, 16 to 65 years old
Amantadine or Rimantadine, usually 100 mg orally, twice a day for 7 days
Treatment of Influenza A infection, symptoms and complications
Shortens the duration of fever by about one day. Does not interrupt transmission. Unknown impact on complications.
Common side effects include nausea, loss of appetite, constipation or diarrhea, and upset stomach for both drugs, while for Amantadine can also have serious effects on the nervous system, leading to concentration difficulties and psychiatric symptoms.
Flu (influenza A virus infection and symptoms).
Symptoms and signs:
Cough, dizziness, fever, headache, nausea, pains, runny nose, sore throat, vomiting and aches.
Ear infection, lung infection, Seizures.
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Amantadine and Rimantadine
Amantadine (trade name Symmetrel, by Endo Pharmaceuticals) is a drug that has U.S. Food and Drug Administration approval for use both as an antiviral and an antiparkinsonian drug. Rimantadine (INN, sold under the trade name Flumadine) is an orally administered antiviral drug used to treat, and in rare cases prevent, influenza virus A infection. Both rimantadine and Amantadine are derivates of adamantane. (source)
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