Unclear
Bottom Line
Flu nose spray vaccine with “live” (weakened) viruses. 2 studies conducted, with 36 adults. Unclear benefits. Irritating side effects and unclear safety. Riskier than flu vaccines with “dead” inactivated viruses.
EVIDENCE | POORLY TESTED
EFFECTIVENESS | UNCLEAR
SAFETY | UNCLEAR SAFETY
Avoid this treatment:
No data exists on benefits. More research is needed. High probability for side effects. May be risky. Consider the flu shot instead, if at all…
Flu nose spray vaccine with “live” (weakened) viruses
Target Population:
Adults with Cystic Fibrosis, 16 to 65 years old
Dosage:
Seasonal vaccine (once a year). 0.2 mL. One dose.
Goal:
Prevention of Influenza infection, symptoms and complications.
Poorly tested
Adults Tested
Benefits:
Unclear. It does evoke immune system response, but it is not clear if this response brings actual benefits (prevention of flu symptoms and flu complications).
Unclear safety
Risks:
Unclear. More research needed. The studies resulted high frequency of side effects, but none were life threatening or persistent. Irritating side effects include: runny nose, sore throat, cough, headache, fever, chills, muscle aches.
Medical problem:
Flu (influenza virus infection and symptoms).
Symptoms and signs:
Cough, dizziness, fever, headache, nausea, pains, runny nose, sore throat, vomiting and aches.
Complications:
Ear infection, lung infection, Seizures.
Additional Information
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Flu Nasal Aerosol
Live attenuated influenza vaccine (LAIV) is a type of influenza vaccine in the form of a nasal spray. It is an attenuated vaccine, unlike most influenza vaccines, which are inactivated vaccines. LAIV is administered intranasally, while inactivated vaccines are administered by intramuscular injection. Both live attenuated and inactivated vaccines are typically trivalent, since they contain material from three different influenza virus. LAIV is sold under the trade name FluMist in the United States and Canada. (source)
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