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Recombinant Influenza vaccine (vaccine) for prevention of seasonal influenza in pregnant Adults

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    Bottom Line

  • Flu shot vaccine with “dead” inactivated viruses. 1 study conducted, with 2,116 pregnant women. Does not seem to prevent flu symptoms and does not prevent flu complications (for mothers and for their babies). Irritating side effects. Unclear safety.

    • -  Evidence icon EVIDENCE | NEEDS MORE TESTING
    • -  Effectiveness icon EFFECTIVENESS | INEFFECTIVE
    • -  Safety Circle icon SAFETY | MILD RISKS -  Tooltip icon Consult a Doctor


Do not use this treatment:

It does not seem to prevent flu symptoms, and it does not prevent flu complications. It has irritating side effects and unclear safety.

Doctors Say That -  Tooltip icon

Note that the information here relates only to healthy pregnant women. Flu vaccines are, for example, essential for asthmatic adults.

About Recombinant Influenza vaccine (vaccine)

Flu shot vaccine with “dead” inactivated viruses

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    Target Population:

    pregnant Adults, 16 to 65 years old

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    Seasonal vaccine (once a year). Most brands - 0.5 mL (Fluzone - 0.25 mL, Fluzone Intradermal - 0.1 mL). One dose.

  • - Goal icon


    Prevention of Influenza infection, symptoms and complications.

Research Summary

  • - Green Pages icon Needs more testing
  • 1 Clinical Studies
  • 2,116 - Tooltip icon Adults Tested
  • Ineffective
  • Benefits:

    Ineffective, according to a single, well conducted randomized controlled trial. Does not prevent Influenza-like symptoms, nor complications (lung infection, hospitalization, mortality) in mothers, newborns and infants. Prevents some confirmed influenza infection (but no noticeable symptoms...). More research is needed.

  • - Safety icon Mild risks
  • Risks:

    Unclear. More research needed. Irritating side effects: soreness, redness, and/or swelling from the shot; headache, fever, cough, nausea, muscle aches, itching, sore eyes.

Influenza virus infection Overview

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    Medical problem:

    Flu (influenza virus infection and symptoms).

  • - Sumptoms icon

    Symptoms and signs:

    Cough, dizziness, fever, headache, nausea, pains, runny nose, sore throat, vomiting and aches.

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    Ear infection, lung infection, Seizures, still birth.

Additional Information

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